Nitrofuran SEM antibiotic residue ELISA test kit

1. Intended use

RIDASCREEN® Nitrofuran (SEM) (product code R3724) is an ELISA kit using a competitive enzyme immunoassay for the quantitative analysis of the antibiotic residue semicarbazide (SEM) in shrimp, fish and meat (beef, pork and chicken).

2. General information

- Nitrofurans are synthetic broad-spectrum antibiotics, often used in livestock farming because of their antibacterial properties and excellent pharmacokinetics. They have also been used as growth promoters when farming shrimp, poultry and pigs. Long-term animal studies have shown that the parent compounds and their metabolites are carcinogenic and mutagenic. This led to a ban on the use of nitrofurans to treat animals used for food production. In 1993 the EU banned the use of the nitrofurans furaltadone, nitrofurantoin and nitrofurazone in food-producing animals, and in 1995 the use of furazolidone was banned as well.

- The analysis of nitrofurans is based on detecting the tissue-bound metabolites of nitrofurans. The parent compounds are difficult to detect accurately because they are metabolised very quickly after treatment. However, nitrofuran metabolites bound to tissue persist for a long time after administration and they are used to detect the misuse of nitrofurans.

- parent compound/metabolite/after derivatisation
Nitrofurantoin / 1-Aminohydantoin – AHD /NP-AHD
Furaltadon / 3-Amino-5-morpholinomethyl-2-oxazolidinon – AMOZ / NP-AMOZ
Furazolidon / 3-Amino-2-oxazolidinon – AOZ /NP -AOZ
Nitrofurazon/Semicarbazide – SEM/NP-SEMP-AOZ
Nitrofurazone / Semicarbazide (SEM) / NP-SEM

Options the customer can choose to buy additionally

- RIDA® Nitrofuran SEM Spiking Solution
- Free software RIDASOFT® Win.NET Food & Feed

4. Specifications of the ELISA kit for Nitrofuran SEM antibiotic residues | RIDASCREEN® Nitrofuran (SEM)

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