ACQUITY QDa II Mass Detector

Separate beyond question with the power of mass detection

Single quadrupole mass detection is a highly reliable technique for many different application areas, yet may be considered by some to be challenging to implement. Easy to use and remarkably robust, the ACQUITY QDa II Mass Detector takes single quadrupole performance to the next level. Complementary to optical detection, the ACQUITY QDa II Mass Detector works in harmony with your chromatography to minimize the risk of unexpected components or co-elutions, and confirm trace sample constituents with confidence in a single workflow.

By adding a compact, stackable, and energy efficient mass detector to complement your chromatography system, you can unlock a new realm of productivity and generate an extra dimension of information from your separation knowing that all your sustainability goals are being addressed, without the cost or complexity of traditional mass spectrometry.

Overview

• Maximize sample information across analytical and purification workflows with a robust optical detector to cover more samples and mitigate the risk of any undetected components for small and large molecules and new modalities
• Maximize system up-time and productivity with a low maintenance stackable system that does not require additional bench space or specialist training
• Eliminate the need for sample-specific user adjustments typical of traditional mass spectrometers for uninterrupted operation
• Gain confidence in the robustness of your separations by adding mass detection to your method development workflow for fast peak tracking and reliable peak purity
• Reduce time developing robust analytical methodologies with industry-leading AQbD method development software

Obtain more information from every sample, faster, and easier

As intuitive as an optical detector and robust enough to handle all of your analyses, the ACQUITY QDa II Mass Detector allows you to cover more compounds and help mitigate the risk of a sample component going undetected for small molecules, large molecules, and new modalities.

Pre-optimized to work with all your samples, you can consistently and routinely achieve more, without the need for sample-specific user adjustments typical of traditional mass spectrometers, or specialist training or expertise. Cleaning and routine maintenance are minimal, maximizing system up-time and productivity making this an ideal choice for QC laboratories wanting a robust and routine instrument.

Have more confidence in the robustness of your separations

The addition of mass detection to your method development workflow enables fast peak tracking and greater confidence in peak purity for more robust separations. Combined with industry leading AQbD method development software, your lab can reduce the time it takes to develop truly robust analytical methodologies.

Prepare your laboratory for the future with sustainable solutions

The ACQUITY QDa II Mass Detector has earned the ACT Environmental Impact Factor Label published by My Green Lab. With up to a 70% reduction in energy consumption and heat output compared to comparable instruments from other vendors, combined with exceptionally low running costs, the ACQUITY QDa II Mass Detector helps you minimize the environmental impact of your laboratory and maximize the efficiency of your operations.

Seamless integration into your environment

Full compatibility with our market-leading Empower Software Solutions lets you seamlessly add mass detection capability to your existing operations, maintaining compliance, and requiring minimal additional training for existing users.

Simplify Biologics Mass Confirmation Directly in Empower

Empower Software in-line deconvolution extends the value of the ACQUITY QDa II Mass Detector for biologics laboratories by converting complex, multiply-charged MS spectra into clear molecular mass information directly within the chromatography workflow. Designed to support intact proteins, antibody drug conjugates (ADC), peptides, glycans, and other large-molecule modalities, this capability helps scientists identify product variants, monitor impurities, and confirm critical quality attributes, without specialist data handling or disconnected software steps.

Keep your laboratory at the forefront of science

The FlexUP Technology Renewal Program enables your laboratory to work with the latest, most advanced instruments. Older technology may limit your performance, increase costs, and open your laboratory to unnecessary risk. Manage the lifecycle of your laboratory’s assets by learning more.